Reconstituted mineralized cartilage tissue
US6464729B1 · kind B1 · utility
42Cited by
22References
11Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Sep 29, 1998 |
| Grant date | Oct 15, 2002 |
| Priority date | — |
| Expiry date | Sep 29, 2018 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S623/919
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A biological material comprising a continuous layer of cartilaginous tissue reconstituted in vitro which contains components associated with cartilage mineralization. The biological material may be cultured with a mineralizing agent to form a mineralized biological material. The mineralized biological material is characterized by having a biochemical composition and physiological organization substantially similar to the deep and contiguous calcified cartilage zones of articular cartilage found in animals in vivo. Methods for preparing the biological materials and methods of using the biological materials are described.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.