MAGE-1 c-terminal immunogenic peptides
US6464980B1 · kind B1 · utility
14Cited by
1References
5Claims
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Key dates
| Filing date | Apr 2, 1996 |
| Grant date | Oct 15, 2002 |
| Priority date | — |
| Expiry date | Apr 2, 2016 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K39/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The complete nucleotide and amino acid sequences of the human MAGE-1 antigen are provided. Peptides from residues of the C-terminal are used to define epitopes that stimulate HLA-restricted cytotoxic T lymphocyte activity against MAGE-1 antigens. The peptides are particularly useful in methods for stimulating the immune response of individuals against MAGE-1 antigens associated with melanomas.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.