Anti-angiogenic agent and method for inhibiting angiogenesis
US6465424B1 · kind B1 · utility
0Cited by
9References
9Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jan 17, 2000 |
| Grant date | Oct 15, 2002 |
| Priority date | — |
| Expiry date | Jan 17, 2020 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2319/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to compositions that inhibit the proliferation and migration of endothelial cells. The compositions contain a pre-activation domain (“PAD”) from plasminogen, or a biologically active fragment thereof, and at least one kringle region from plasminogen, or a biologically active portion thereof. The compositions are useful to treat angiogenic associated disorders.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.