Microencapsulation and sustained release of biologically active acid-stable or free sulfhydryl-containing proteins
US6465425B1 · kind B1 · utility
38Cited by
22References
53Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Feb 10, 2000 |
| Grant date | Oct 15, 2002 |
| Priority date | — |
| Expiry date | Feb 10, 2020 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/215
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
This invention relates to sustained release compositions, and methods of forming and using said compositions, for the sustained release of biologically active acid-stable or free sulfhydryl-containing proteins, in particular &bgr;-IFN. The sustained release composition of this invention comprises a biocompatible polymer having dispersed therein a stabilized biologically active acid-stable or free sulfhydryl-containing protein formulation and a nonionic polymer surfactant.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.