Antimicrobial cationic peptides
US6465429B1 · kind B1 · utility
21Cited by
19References
1Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jun 13, 2000 |
| Grant date | Oct 15, 2002 |
| Priority date | — |
| Expiry date | Jun 13, 2020 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02A50/30
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A novel class of cationic peptides having antimicrobial activity is provided. Examples of such peptides include [NH2]kWKSFIKKLTTAVKKVLTTGLPALIS[COOH] (SEQ ID NO:1) and [NH2]KWKSFIKKLTSAAKKVVTTAKPLISS[COOH] (SEQ ID NO:2). Also provided are methods for inhibiting the growth of bacteria utilizing the peptides of the invention. The peptides are particularly useful for inhibiting endotoxemia in a subject.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.