Process for preparing malonate derivatives or &bgr;-keto esters from epoxide derivatives
US6465680B2 · kind B2 · utility
2Cited by
8References
26Claims
0Family size
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Key dates
| Filing date | Jun 20, 2001 |
| Grant date | Oct 15, 2002 |
| Priority date | — |
| Expiry date | Jun 20, 2021 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C67/37
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A process for preparing a malonic acid monoester or &bgr;-ketoester from an epoxide includes the steps of reacting an epoxide with carbon monoxide and an alcohol in the presence of a catalytic amount of a cobalt compound and at least one promoter to produce a &bgr;-hydroxyester, separating the &bgr;-hydroxyester from the cobalt compound and the promoter, and oxidizing the &bgr;-hydroxyester to produce a malonic acid monoester or &bgr;-ketoester.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.