Patent · US Expired

Metal-catalyzed arylations of hydrazines, hydrazones, and related substrates

US6465693B2 · kind B2 · utility

57Cited by

3References

20Claims

0Family size

Assignee

Massachusetts Institute of Technology · US

Inventors

Stephen L. Buchwald · Newton, US
Seble H. Wagaw · Lake Bluff, US
O. Geis · Berlin, DE

Key dates

Filing date	Jan 18, 2001
Grant date	Oct 15, 2002
Priority date	—
Expiry date	Jan 18, 2021

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D401/04
WIPO fieldOrganic fine chemistry
WIPO sectorChemistry

Abstract

A method is provided for the transition metal-catalyzed arylation, or vinylation, of hydrazines, hydrazones, and the like. Additionally, the invention provides a conceptually novel strategy, the cornerstone of which is the transition metal-catalyzed arylation or vinylation method, for the synthesis of indoles, carbazoles, and the like. The methods and strategies of the invention may be utilized in standard, parallel, and combinatorial synthetic protocols.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.