Patent · US Expired

Methods of screening nucleic acids using volatile salts in mass spectrometry

US6468748B1 · kind B1 · utility

113Cited by

129References

23Claims

0Family size

Assignee

Sequenom, Inc. · US

Inventors

Joseph Monforte · Berkeley, US
Thomas Shaler · Fremont, US
Yuping Tan · Fremont, US
Christopher Becker · Palo Alto, US

Key dates

Filing date	Feb 29, 2000
Grant date	Oct 22, 2002
Priority date	—
Expiry date	Feb 29, 2020

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12Q1/683
WIPO fieldBiotechnology
WIPO sectorChemistry

Abstract

This invention relates to methods for screening nucleic acids for mutations by analyzing nonrandomly fragmented nucleic acids using mass spectrometric techniques and to procedures for improving mass resolution and mass accuracy of these methods of detecting mutations.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.