Agent and method for detecting chemical substances
US6468752B1 · kind B1 · utility
Assignee
Inventor
Key dates
| Filing date | Nov 13, 2000 |
| Grant date | Oct 22, 2002 |
| Priority date | — |
| Expiry date | Nov 13, 2020 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q1/6818
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The invention relates to an agent for detecting chemical substances, comprising: a first polynucleotide or peptide sequence having a first fluorophore molecule, the first end of said sequence being bonded on a solid phase and a second polynucleotide or peptide sequence having a second fluorophore molecule, the second end of said sequence having a group that is sensitive to the chemical substance to be detected. The first polynucleotide or peptide sequence can be hybridized to the second polynucleotide or peptide sequence in such a way that a spatial relationship enabling an interaction betweeen the first and the second fluorophore molecule is produced. When the chemical substance including a physical property is attached to the group and the influence of an external force is exerted on the physical property, the spatial relation can be eliminated, thereby generating or abolishing a fluorescent reaction.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.