Methods of preserving prokaryotic cells and compositions obtained thereby
US6468782B1 · kind B1 · utility
41Cited by
24References
23Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Dec 4, 1997 |
| Grant date | Oct 22, 2002 |
| Priority date | — |
| Expiry date | Dec 4, 2017 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N1/04
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
This invention provides methods of drying and stabilizing prokaryotic cells, and the compositions obtained thereby. The cells are first cultured or incubated under conditions sufficient to induce intracellular trehalose, suspended in a stabilizing solution and dried to form a solid glass. The resulting product is storage-stable at room temperature, showing little viability loss on storage.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.