Peroral dosage form for peptide containing medicaments, in particular insulin

US6468959B1 · kind B1 · utility

Assignee

• ALFATEC-Pharm GmbH · DE

Inventors

• Jens-Christian Wunderlich · Heidelberg, DE
• Ursula Schick · Schriesheim, DE
• Jurgen Freidenreich · Schriesheim, DE
• Jurgen Werry · Ludwigshafen, DE

Key dates

• Filing date: Apr 5, 1994
• Grant date: Oct 22, 2002
• Expiry date: Apr 5, 2014

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61K9/4891
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

There is provided a plural dosage form for peptide pharmaceuticals comprising a matrix of gelatin or gelatin derivative having distributed therein the peptide pharmaceutical in particular insulin, as well as, pharmaceutically conventional carriers and additives. By selection of the appropriate gelatin the pharmaceutical is liberated in the small intestine or the large intestine so that is not enzymatically degraded anymore by peptidases.