7-hexanoyltaxol and methods for preparing the same
US6469050B1 · kind B1 · utility
1Cited by
12References
12Claims
0Family size
Inventors
Key dates
| Filing date | Oct 16, 2000 |
| Grant date | Oct 22, 2002 |
| Priority date | — |
| Expiry date | Oct 16, 2020 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P35/02
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
An antitumor compound of formula (5): Also provided by the present invention is a method of preparing a compound of formula (5) whereby diesterification of the alcohol groups located at the 2′and 7 positions of paclitaxel is followed by the hydrolysis of the 2′hexanoate group resulting in 7-hexanoyltaxol.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.