Radiopharmaceutical products suitable for the selective labeling of lymphocytes, and their preparation
US6469146B1 · kind B1 · utility
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17Claims
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Key dates
| Filing date | May 31, 2000 |
| Grant date | Oct 22, 2002 |
| Priority date | — |
| Expiry date | May 31, 2020 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P35/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention concerns radiopharmaceutical products suitable for the selective labeling of lymphomas containing a metal complex with the formula:[M(R1CS2)(R1CS3)2]in which M is chosen from among 99mTc, 186Re and 188Re, and R1 represents an alkyl, cycloalkyl, aralkyl or aryl group, optionally substituted, obtained by reaction of a pertechnetate or a perrhenate with a reducing agent such as SnCl2ZP2O in the presence of a dithiocarboxylate having the formula: (R1CS2)−Z2+.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.