Method for calibrating spectrophotometric apparatus with synthetic fluids to measure plasma and serum analytes
US6470279B1 · kind B1 · utility
Inventor
Key dates
| Filing date | Nov 23, 1999 |
| Grant date | Oct 22, 2002 |
| Priority date | — |
| Expiry date | Nov 23, 2019 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N21/274
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Described is a method for calibrating a spectrophotometric apparatus which is used to measure analytes in plasma and/or serum samples based on the calibration of a First Apparatus, and for recalibrating such apparatus, including recalibration of the First Apparatus all using synthetic calibrators. These apparatus use absorption of radiation to measure analytes in serum or plasma samples. The method described includes using synthetic calibrators which are submitted to the First Apparatus for measurement and compared with measurements of similar calibrators in a Second Apparatus and using the comparison to derive concentrations of analytes in samples measured on the Second Apparatus. As an alternative to making all apparatus identical, in terms of wavelength calibration, the absorbances of all apparatus should be mapped onto a standard set of wavelengths.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.