Compounds and methods for modulating OB-cadherin mediated cell adhesion
US6472367B1 · kind B1 · utility
12Cited by
8References
14Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | May 5, 1998 |
| Grant date | Oct 29, 2002 |
| Priority date | — |
| Expiry date | May 7, 2018 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S977/91
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Modulating agents for inhibiting or enhancing OB-cadherin mediated cell adhesion are provided. The modulating agents comprise one or more of: (a) an OB-cadherin CAR sequence; (b) a peptide analogue or peptidomimetic thereof; (c) an antibody or antigen-binding fragment thereof that specifically binds an OB-cadherin CAR sequence; and/or (d) a polynucleotide encoding any of the foregoing peptide sequences. Methods for using such modulating agents for modulating OB-cadherin-mediated cell adhesion in a variety of contexts are also provided.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.