Patent · US Expired

Medical diagnostic ultrasound-aided drug delivery system and method

US6475148B1 · kind B1 · utility

69Cited by
12References
38Claims
0Family size

Assignee

Inventors

Key dates

Filing dateOct 25, 2000
Grant dateNov 5, 2002
Priority date
Expiry dateDec 13, 2020

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61M37/0092
  • WIPO fieldMedical technology
  • WIPO sectorInstruments

Abstract

A method and system is provided for delivering drugs carried by microspheres. A medical diagnostic ultrasound system destroys microspheres in a specific localized area or at a specific time. A region of interest that is a subset of an imaged area is identified for destroying drug-carrying microspheres. The transmit beamformer is configured to transmit acoustic energy for destroying microspheres within that area while minimizing the destruction of microspheres outside of the region of interest. A multidimensional transducer array may provide focusing in three-dimensions for accurately destroying microspheres in the specific region while minimizing the destruction of microspheres outside that region. A trigger responsive to a heart or breathing cycle may control when microspheres are destroyed, providing delivery of drugs at the most opportune time in the cycle.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.