Sequence specific detection of nucleic acids using a solid carrier bound with nucleic acid analog probes

US6475721B2 · kind B2 · utility

Assignee

• Boston Probes, Inc. · US

Inventors

• Jorg Kleiber · Penzberg, DE
• Henrik Ørum · Neubiberg, DE
• Ane-Ullerup Lester · Krakow am See, DE
• Albert Geiger · Fort Saskatchewan, CA

Key dates

• Filing date: Nov 12, 1997
• Grant date: Nov 5, 2002
• Expiry date: Nov 12, 2017

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12Q1/6832
• WIPO field: Biotechnology
• WIPO sector: Chemistry

Abstract

A method for the detection of point mutation and polymorphisms in nucleic acids or for sequencing of unknown nucleic acids by a simple procedure using arrays uses nucleic acid analoges as sequence discriminators. This procedure simplifies the working mode in complex problematic cases.