Patent · US Expired

Recombinant cell clones having increased stability and methods of making and using the same

US6475725B1 · kind B1 · utility

60Cited by

7References

34Claims

0Family size

Assignee

Baxter Aktiengesellschaft · AT

Inventors

Manfred Reiter · Wien, AT
Wolfgang Mundt · Wien, AT
Friedrich Dorner · Wien, AT

Key dates

Filing date	Jun 2, 1999
Grant date	Nov 5, 2002
Priority date	—
Expiry date	Jun 2, 2019

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12N2531/00
WIPO fieldBiotechnology
WIPO sectorChemistry

Abstract

Disclosed are stable recombinant cell clones which are stable in serum- and protein-free medium for at least 40 generations, a biomass obtained by multiplying the stable cell clone under serum- and protein-free culturing conditions, and a method of preparing recombinant proteins by means of the biomass. Furthermore, the invention relates to a method of recovering stable recombinant cell clones.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.