Patent · US Expired

Genetically modified cells and methods for expressing recombinant heparanase and methods of purifying same

US6475763B1 · kind B1 · utility

19Cited by
0References
8Claims
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Assignee

Inventors

Key dates

Filing dateJan 19, 2000
Grant dateNov 5, 2002
Priority date
Expiry dateJan 19, 2020

Classification

  • Technology area (CPC G)Physics
  • CPC primaryG01N2400/40
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Bacterial, yeast and animal cells and methods for overexpressing recombinant heparanase in cellular systems, methods of purifying recombinant heparanase therefrom and modified heparanase species which serve as precursors for generating highly active heparanase by proteolysis.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.