P element derived vector and methods for its use
US6475798B2 · kind B2 · utility
Assignees
Inventors
Key dates
| Filing date | Aug 9, 2001 |
| Grant date | Nov 5, 2002 |
| Priority date | — |
| Expiry date | Aug 9, 2021 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2800/90
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Novel P element derived vectors and methods for their use to insert an exogenous nucleic acid into the genome of a target cell are provided. The subject vectors have a pair of P element transposase recognized insertion sites, e.g. 31 base pair inverted repeats, flanking at least two transcriptionally active genes. In practicing the subject methods, a vector of the subject invention is introduced into the target cell under conditions sufficient for transposition to occur. The subject methods find use in a variety of applications in which the insertion of an exogenous nucleic acid into the genome of a target cell is desired, e.g. include research, synthesis and therapeutic applications.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.