Composition and dosage form for delayed gastric release of alendronate and/or other bis-phosphonates
US6476006B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Jan 26, 2001 |
| Grant date | Nov 5, 2002 |
| Priority date | — |
| Expiry date | Jan 26, 2021 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K9/286
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides compacted pharmaceutical composition for oral administration to a patient which expands upon contact with gastric fluid to retain a dosage form in the patient's stomach for an extended period of time, the formulation comprising a non-hydrated hydrogel, a superdisintegrant and tannic acid. The present invention further provides a pharmaceutical dosage form containing an active ingredient, and the compacted pharmaceutical composition. The invention further provides a dosage form suitable for delivering a therapeutic bis-phosphonate such as alendronate to the stomach of a patient over and extended period.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.