7-alkyl- and cycloalkyl-substituted imidazotriazinones

US6476029B1 · kind B1 · utility

Assignee

• BAYER HEALTHCARE LLC · DE

Inventors

• Ulrich Niewohner · Wermelskirchen, DE
• Mazen Es-Sayed · Langenfeld, DE
• Helmut Haning · Milford, US
• Thomas Schenke · Odenthal, DE
• Gunter Schmidt · Houghton, US
• Karl-Heinz Schlemmer · Wuppertal, DE
• Erwin Bischoff · Wuppertal, DE
• Klaus Dembowsky · Boston, US
• Elisabeth Perzborn · Wuppertal, DE

Key dates

• Filing date: Mar 23, 2001
• Grant date: Nov 5, 2002
• Expiry date: Mar 23, 2021

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07F9/6561
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention relates to 7-alkyl- and cycloalkyl-substituted imidazotriazinones, to processes for their preparation and to their use as medicaments, in particular as inhibitors of cGMP-metabolizing phosphodiesterases.