Patent · US Expired

Estrogen receptor ligands

US6476196B1 · kind B1 · utility

5Cited by

0References

9Claims

0Family size

Assignee

Kara Bio AB · SE

Inventors

Jan Ljunggren · Solna, SE
Ann-Gerd Thorsell · Stockholm, SE
Owe Engstrom · Nacka, SE
Tomas Bonn · Huddinge, SE
Mats Carlquist · Sundbyberg, SE
Andrzeji Brzozowski · York, GB
Ashley Pike · York, GB
Roderick Hubbard · York, GB

Key dates

Filing date	Apr 27, 2001
Grant date	Nov 5, 2002
Priority date	—
Expiry date	Apr 27, 2021

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07K2299/00
WIPO fieldBiotechnology
WIPO sectorChemistry

Abstract

The present invention is directed to crystals of ER&bgr; ligand binding domain complexed with (1) N-(n-butyl)-11-[3,17&bgr;-dihydroxyestra-1,3,5(10)-trien-7&agr;-yl]N-methylundecanamide; estradiol and a peptide comprising the amino acid sequence LXXLL; or 17-epiestriol and a peptide comprising the amino acid sequence LXXLL.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.