Heterocyclic benzenesulphonamide compounds as bradykinine antagonists
US6479515B1 · kind B1 · utility
1Cited by
16References
20Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jul 24, 2001 |
| Grant date | Nov 12, 2002 |
| Priority date | — |
| Expiry date | Jul 24, 2021 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D249/08
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention concerns compounds selected among the group consisting of (i) compounds of formula (I) wherein: Het1 represents a nitrogenous heterocycle with 5 apices, in particular imidazole, pyrazole, or triazole; Het2 represents a nitrogenous heterocycle with 4, 5 or 6 apices, selected among the heterocycles: (II) wherein R1 and R2 are defined as mentioned in the description; and (ii) their additive salts. The invention also concerns the method for preparing said compounds and their use in therapy, in particular for treating pathologies involving bradykinine.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.