Substituted stilbenes as glucose uptake enhancers

US6479548B2 · kind B2 · utility

Assignee

• Telik, Inc. · US

Inventors

• John W. Patterson · Maple Valley, US
• Sophia Park · Emeryville, US
• Robert T. Lum · Palo Alto, US
• Wayne Spevak · Berkeley, US

Key dates

• Filing date: May 31, 2001
• Grant date: Nov 12, 2002
• Expiry date: May 31, 2021

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D317/60
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

Compound of formula I activate the insulin receptor kinase. Pharmaceutical compositions comprising the compounds, and methods of treatment of hyperglycemia and other diseases involving imbalance of glucose levels, especially for the treatment of type II diabetes, by administering these compounds to mammalian hosts, and processes for their preparation, are also described.