Temperature sensitive gel for sustained delivery of protein drugs
US6482435B1 · kind B1 · utility
45Cited by
33References
10Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jan 15, 1999 |
| Grant date | Nov 19, 2002 |
| Priority date | — |
| Expiry date | Jan 15, 2019 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K47/10
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Pharmaceutical compositions for the delivery of pharmacologically active proteins are provided by the present invention. The compositions of the present invention comprise a polymeric matrix having thermal gelation properties in which is incorporated a discrete suspension of at least one biologically active macromolecular polypeptide which retains greater than 90 percent of its biological activity. Furthermore, the concentration of the macromolecular polypeptide is greater than 0.5 percent by weight of the composition.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.