Fiber optic biosensor for selectively detecting oligonucleotide species in a mixed fluid sample
US6482593B2 · kind B2 · utility
141Cited by
45References
19Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Nov 5, 1998 |
| Grant date | Nov 19, 2002 |
| Priority date | — |
| Expiry date | Nov 5, 2018 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S977/924
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The present invention provides biosensors, apparatus and methods for selectively detecting at least one complementary oligonucleotide target specie in a fluid sample containing a mixture of different oligonucleotide fragments. One preferred embodiment of the biosensor is as a unitary fiber optic array having species of single stranded nucleic acid disposed as individual deposits in aligned organization upon multiple strand end faces at differing spatial positions on the distal array end surface.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.