Polymer packing material for liquid chromatography and a producing method thereof
US6482867B1 · kind B1 · utility
Assignee
Inventors
Key dates
| Filing date | Aug 20, 1999 |
| Grant date | Nov 19, 2002 |
| Priority date | — |
| Expiry date | Aug 20, 2019 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC08J2325/02
- WIPO fieldChemical engineering
- WIPO sectorChemistry
Abstract
There are disclosed a polymer packing material suitable for liquid chromatography and a producing method thereof. The polymer packing material having a polymer particle based on a styrene skeleton with monodispersed particle distribution can be obtained by hydrophilic treatment of an inner surface of a micropore existing in a fine pore of the polymer packing material, or subsequent introduction of a hydrophobic group into the inner hydrophilic surface by chemical modification. A method of producing the polymer packing material suitable for liquid chromatography includes the step of polymerizing glycerol dimethacrylate as a crosslinking agent and 2-ethylhexl methacrylate as a monomer according to a two-step swelling polymerization process. Alternatively, the producing method includes the step of crosslinking and polymerizing only glycerol dimethacrylate to form a polymer, and introducing the hydrophobic group into the polymer by chemical modification.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.