Patent · US Expired

Method and apparatus for preparing Bi-213 for human therapeutic use

US6485695B1 · kind B1 · utility

2Cited by

5References

5Claims

0Family size

Assignee

European Community (EC) · LU

Inventors

Lothar Koch · Weingarten, DE
Christos Apostolidis · Heidelberg, DE
Roger Molinet · Blankenloch, DE
Bruno Brandalise · Blankenloch, DE
Willem Janssens · Hamm (Sieg), DE
Jacques Van Geel · Ettlingen, DE

Key dates

Filing date	May 4, 2000
Grant date	Nov 26, 2002
Priority date	—
Expiry date	May 4, 2020

Classification

Technology area (CPC G)Physics
CPC primaryG21G4/08
WIPO fieldEngines, pumps, turbines
WIPO sectorMechanical engineering

Abstract

This invention relates to a method and an apparatus for preparing Bi-213 to be integrated in a radioimmunocojugate for human therapeutic use. According to the invention the method comprises the sequence of steps as follows: a) an ampoule 5 containing colloid-free actinium-225, obtained from drying an actinium nitrate solution, is loaded into a container 20 provided with radiation panels 21; b) a dissolving medium is poured into the ampoule 5; c) the solution obtained in the ampoule is transferred into an ion exchange column 6; d) an elution medium is circulated through the column 6; e) the eluate containing eluted Bi-213 is pumped towards a vial 10 for quantification and quality control.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.