Patent · US Expired

Once daily pharmaceutical tablet having a unitary core

US6485748B1 · kind B1 · utility

31Cited by
51References
14Claims
0Family size

Assignee

Inventors

Key dates

Filing dateDec 12, 1997
Grant dateNov 26, 2002
Priority date
Expiry dateDec 12, 2017

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61K9/2886
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

A controlled release tablet is disclosed which comprises:(a) a homogeneous compressed core which comprises:(i) a medicament which is very slightly soluble to practically insoluble in water at 25° C.;(ii) a water soluble osmotic compound(iii) one or more osmotic polymers; and(b) a membrane coating which completely covers said core tablet which comprises a mixture of a:(i) a water insoluble pharmaceutically acceptable polymer; and(ii) a pH dependent polymer such as an enteric coating polymer, the weight ratio of the pH dependent polymer to the water insoluble pharmaceutically acceptable polymer being 0.1:1 to 0.75:1.A controlled release tablet which comprises:(a) a medicament(a) a homogeneous compressed core which comprises:(i) a medicament;(ii) a water soluble osmotic compound(iii) one or more osmotic polymers; and(b) a membrane coating which completely covers said core tablet which comprises a mixture of:(i) a water insoluble pharmaceutically acceptable polymer; and(ii) an enteric polymer.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.