Patent · US Expired

Method for inhibiting CD95-independent apoptosis in AIDS

US6485929B1 · kind B1 · utility

2Cited by

0References

10Claims

0Family size

Assignee

DEUTSCHES KREBSFORSCHUNGSZENTRUM STIFTUNG DES ÖFFENTLICHEN RECHTS · DE

Inventors

Peter Krammer · Heidelberg, DE
Christina Berndt · Hersbruck, DE

Key dates

Filing date	Oct 11, 2000
Grant date	Nov 26, 2002
Priority date	—
Expiry date	Oct 11, 2020

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61K38/00
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The invention relates to a method for inhibiting CD95-independent apoptosis, comprising the following steps:(a) blocking the bonding of HIV-1 gp120 on receptors CD4 and/or CXCR4 or of a factor competing for this bonding, and/or(b) inhibiting the signal path induced by the bonding of (a).The invention also relates to a system for identifying substances which can be utilized for inhibiting CD95-independent apoptosis.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.