Anticancer compounds: process for their preparation and pharmaceutical compositions containing them

US6486196B2 · kind B2 · utility

Assignee

• Dr. Reddy's Research Foundation · IN

Inventors

• Srinivas Nanduri · Hyderabad, IN
• Sairam Pothukuchi · Hyderabad, IN
• Sriram Rajagopal · Darsi, IN
• Venkateswarlu Akella · Darsi, IN
• Sunilkumar Bhadramma Kochunarayana Pillai · Hyderabad, IN
• Ranjan Chakrabarti · Hyderabad, IN

Key dates

• Filing date: May 4, 2001
• Grant date: Nov 26, 2002
• Expiry date: May 4, 2021

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D307/34
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

The present invention relates to novel anticancer agents, their stereoisomers, their polymorphs, their pharmaceutically acceptable salts, and their pharmaceutically acceptable solvates. The present invention more particularly relates to novel derivatives of andrographolide, their stereoisomers, their polymorphs, their pharmaceutically acceptable salts, and their pharmaceutically acceptable solvates. The novel derivatives of andrographolide have the general formula (I).