Non-polar media for polynucleotide separations
US6488855B2 · kind B2 · utility
12Cited by
28References
32Claims
0Family size
Assignee
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Key dates
| Filing date | Apr 5, 2001 |
| Grant date | Dec 3, 2002 |
| Priority date | — |
| Expiry date | Jun 15, 2021 |
Classification
- Technology area (CPC B)Performing Operations; Transporting
- CPC primaryB01J20/328
- WIPO fieldChemical engineering
- WIPO sectorChemistry
Abstract
Nonporous beads having an average diameter of about 0.5-100 microns are suitable for chromatographic separation of mixtures of polynucleotides when the beads comprise a nonporous particle which are coated with a polymer or which have substantially all surface substrate groups endcapped with a non-polar hydrocarbon or substituted hydrocarbon group. The beads provide efficient separation of polynucleotides using Matched Ion Polynucleotide Chromatography.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.