Patent · US Expired

Hot-melt extrudable pharmaceutical formulation

US6488963B1 · kind B1 · utility

257Cited by
8References
6Claims
0Family size

Assignee

Inventors

Key dates

Filing dateMar 2, 1999
Grant dateDec 3, 2002
Priority date
Expiry dateMar 2, 2019

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61K9/2095
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The present invention relates to pharmaceutical formulations comprising a hot-melt extrudable mixture of a therapeutic compound and a high molecular weight poly(ethylene oxide) in an essentially non-film like preparation. In some embodiments, the formulation further comprises poly(ethylene glycol). The present invention also includes efficient methods for hot-melt extruding pharmaceutical formulations in essentially non-film preparations.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.