Methods for identifying chemical compounds that inhibit dissociation of FKBP12.6 binding protein from type 2 ryanodine receptor
US6489125B1 · kind B1 · utility
9Cited by
0References
17Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | May 10, 2000 |
| Grant date | Dec 3, 2002 |
| Priority date | — |
| Expiry date | May 10, 2020 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2800/326
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
This invention provides methods of regulating contraction of a subject's heart and of treating heart failure and cardiac arrhythmia. This invention also provides methods of obtaining compounds that bind to, and activate or inhibit the activation of a type 2 ryanodine (RyR2) receptor, and methods for screening for compounds that alleviate heart disease.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.