Methods and compositions for producing viral particles
US6489142B1 · kind B1 · utility
6Cited by
0References
26Claims
0Family size
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Inventors
Key dates
| Filing date | Jan 25, 2001 |
| Grant date | Dec 3, 2002 |
| Priority date | — |
| Expiry date | Jan 25, 2021 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2840/20
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The invention concerns methods and constructs for producing retroviral particles, in vitro, ex vivo or in vivo. It also concerns the use of said methods and constructs for transferring nucleic acids into cells. More particularly, the invention concerns a composition comprising the whole set of genetic elements required for constituting a retroviral particle, incorporated in one or several recombinant adenoviruses defective for all or part of the regions E1 and E4 at least (adenoviral/retroviral chimeric vectors).
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.