Amidine derivatives as inhibitors of nitric oxide synthase
US6489322B1 · kind B1 · utility
3Cited by
2References
23Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | May 21, 1998 |
| Grant date | Dec 3, 2002 |
| Priority date | — |
| Expiry date | May 21, 2018 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P43/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
There are provided novel compounds of formula (I) wherein R1 represents a 2-thienyl or 3-thienyl ring and R2 represents hydrogen or C 1 to 4 alkyl and optical isomers and racemates thereof and pharmaceutically acceptable salts thereof; together with processes for their preparation, compositions containing them and their use in therapy. The compounds are selective inhibitors of the neuronal isoform of nitric oxide synthase.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.