Patent · US Expired

Heterocyclic compounds useful as inhibitors of tyrosine kinases

US6489328B2 · kind B2 · utility

15Cited by
2References
21Claims
0Family size

Assignee

Inventors

Key dates

Filing dateAug 2, 2001
Grant dateDec 3, 2002
Priority date
Expiry dateAug 2, 2021

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61P43/00
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Disclosed are novel compounds of formula (I): wherein Ar1, X, Y, P, Q and Het are defined herein, which are useful as inhibitors of certain protein tyrosine kinases and are thus useful for treating diseases resulting from inappropriate cell proliferation, which include autoimmune diseases, chronic inflammatory diseases, allergic diseases, transplant rejection and cancer, as well as conditions resulting from cerebral ischemia, such as stroke. Also disclosed are pharmaceutical compositions comprising these compounds, processes for preparing these compounds and novel intermediate compounds useful in these processes.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.