3-alkyl substituted pyrrolidine modulators of chemokine receptor activity
US6489354B1 · kind B1 · utility
5Cited by
8References
16Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Mar 1, 2000 |
| Grant date | Dec 3, 2002 |
| Priority date | — |
| Expiry date | Mar 1, 2020 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D409/14
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention is directed to pyrrolidine compounds of the formula I: (wherein R1, R2, R3, R4c, R4d, and R4f are defined herein) which are useful as modulators of chemokine receptor activity. In particular, these compounds are useful as modulators of the chemokine receptors CCR-3 and/or CCR-5.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.