Patent · US Expired

DNA-based transposon system for the introduction of nucleic acid into DNA of a cell

US6489458B2 · kind B2 · utility

98Cited by

7References

64Claims

0Family size

Assignee

Regents of the University of Minnesota · US

Inventors

Perry Hackett · Saint Paul, US
Zoltan Ivics · Berlin, DE
Zsuzsanna Izsvak · Berlin, DE

Key dates

Filing date	Sep 10, 1998
Grant date	Dec 3, 2002
Priority date	—
Expiry date	Sep 10, 2018

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12N15/90
WIPO fieldBiotechnology
WIPO sectorChemistry

Abstract

This invention relates to a system for introducing nucleic acid into the DNA of a cell. The system includes the use of a member of the SB family of transposases (SB) or nucleic acid encoding the transposase and a nucleic acid fragment that includes a nucleic acid sequence with flanking inverted repeats. The transposase recognizes at least a portion of an inverted repeats and incorporates the nucleic acid sequence into the DNA. Methods for use of this system are discussed.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.