Patent · US Expired

4-amino substituted-2-substituted-1,2,3,4-tetrahydroquinolines

US6489478B1 · kind B1 · utility

39Cited by
8References
15Claims
0Family size

Assignee

Inventors

Key dates

Filing dateSep 27, 2000
Grant dateDec 3, 2002
Priority date
Expiry dateSep 27, 2020

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D417/12
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Cholesteryl ester transfer protein inhibitors, pharmaceutical compositions containing such inhibitors and the use of such inhibitors to elevate certain plasma lipid levels, including high density lipoprotein-cholesterol and to lower certain other plasma lipid levels, such as LDL-cholesterol and triglycerides and accordingly to treat diseases which are exacerbated by low levels of HDL cholesterol and/or high levels of LDL-cholesterol and triglycerides, such as atherosclerosis and cardiovascular diseases in some mammals, including humans.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.