Microfabricated devices for the delivery of molecules into a carrier fluid

US6491666B1 · kind B1 · utility

Assignee

• MicroCHIPS, Inc. · US

Inventors

• John T. Santini, Jr. · North Chelmsford, US
• Charles Hutchinson · Canaan, US
• Scott A. Uhland · San Jose, US
• Michael J. Cima · Winchester, US
• Robert S. Langer · Newton, US
• Dennis Ausiello · Wellesley, US

Key dates

• Filing date: Nov 17, 2000
• Grant date: Dec 10, 2002
• Expiry date: Dec 18, 2020

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61M2205/8225
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Apparati and methods are provided for the delivery of molecules to a site via a carrier fluid. The apparati include microchip devices which have reservoirs containing the molecules for release. The apparati and methods provide for active or passive controlled release of the molecules. Preferred embodiments include systems for intravenous administration of drugs, wherein drug molecules are released from the microchip devices into a carrier fluid ex vivo, such as a saline solution, forming a drug/saline solution mixture which is then delivered to a patient intravenously.