Patent · US Expired

Glycoconjugates from modified camptothecin derivatives (20-O-linkage)

US6492335B1 · kind B1 · utility

4Cited by

1References

11Claims

0Family size

Assignee

BAYER HEALTHCARE LLC · DE

Inventors

Hans-Georg Lerchen · Leverkusen, DE
Karsten von dem Bruch · Leverkusen, DE
Jörg Buamgarten · Wuppertal, DE
Michael Sperzel · Wuppertal, DE

Key dates

Filing date	Mar 24, 1999
Grant date	Dec 10, 2002
Priority date	—
Expiry date	Mar 24, 2019

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61K38/00
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present invention relates to glycoconjugates of camptothecin derivatives in which at least one carbohydrate component is linked via suitable spacers with the 20-hydroxyl group of a camptothecin derivative. The invention furthermore relates to processes for preparing the compounds according to the invention and to their use as medicaments, in particular in connection with cancer.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.