Compositions comprising D-chiro inositol and sulfonylureas and methods of treatment thereof
US6492339B1 · kind B1 · utility
Assignee
Inventors
Key dates
| Filing date | Oct 26, 2001 |
| Grant date | Dec 10, 2002 |
| Priority date | — |
| Expiry date | Oct 26, 2021 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K31/7004
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides compositions comprising synergistically effective amounts of D-chiro-inositol and sulfonylureas. The present invention also provides methods to treat a subject with insulin resistance comprising administration of D-chiro-inositol and sulfonylurea, either as concurrent single agents or as a combined composition. In particular the methods of the present invention are useful in maintaining pancreatic beta cell function/viability and thus delay diabetes progression. The methods and compositions of the present invention are particularly efficacious in treating insulin resistant subjects with a fasting blood glucose level of less than or equal to 180 mg/dL.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.