Porcine adenovirus type 3 genome
US6492343B1 · kind B1 · utility
Assignee
Inventors
Key dates
| Filing date | Apr 14, 1999 |
| Grant date | Dec 10, 2002 |
| Priority date | — |
| Expiry date | Apr 14, 2019 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2710/10362
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The complete nucleotide sequence of the genome of porcine adenovirus type 3 (PAV-3) is provided. Methods for construction of infectious PAV genomes by homologous recombination in procaryotic cells are provided. Recombinant PAV viruses are obtained by transfection of mammalian cells with recombinant PAV genomes. The PAV-3 genome can be used as a vector for the expression of heterologous nucleotide sequences, for example, for the preparation and administration of subunit vaccines to swine or other mammals. In addition, PAV-3 vectors can be used for gene therapy and expression of heterologous polypeptides. PAV-3 genome sequences can also be used for diagnostic purposes, to detect the presence of PAV-3 DNA in a subject or biological sample.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.