Patent · US Expired

Racemic thioesters for production of polyketides

US6492562B1 · kind B1 · utility

12Cited by
2References
17Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJan 27, 2000
Grant dateDec 10, 2002
Priority date
Expiry dateJan 27, 2020

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07C327/30
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

Facile methods for preparing diketide and triketide thioesters are disclosed. The resulting thioesters may be used as intermediates in the synthesis of desired polyketides, and may contain functional groups which ultimately reside in side chains on the resulting polyketide and thus can be used further to manipulate the polyketide so as form derivatives. The polyketides produced may also be tailored by glycosylation, hydroxylation and the like. New polyketides and their derivatives and tailored forms are thereby produced.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.