Humanized anti-tag-72 monoclonal antibodies using human subgroup 4 kappa light chains

US6495137B1 · kind B1 · utility

Assignee

• THE DOW CHEMICAL COMPANY · US

Inventors

• Peter Mezes · Old Lyme, US
• Ruth A. Richard · Midland, US
• Kimberly Johnson · New York, US
• Jeffrey Schlom · Potomac, US
• Syed V. S. Kashmiri · North Potomac, US
• Liming Shu · Gaithersburg, US
• Eduardo A. Padlan · Kensington, US

Key dates

• Filing date: Oct 30, 1997
• Grant date: Dec 17, 2002
• Expiry date: Oct 30, 2017

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y10S530/867
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Novel composite and humanized anti-TAG-72 monoclonal antibodies, antibody fragments, and derivatives thereof using human subgroup IV kappa light chain framework regions.