PRRSV antigenic sites identifying peptide sequences of PRRS virus for use in vaccines or diagnostic assays
US6495138B1 · kind B1 · utility
34Cited by
11References
3Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Nov 5, 1999 |
| Grant date | Dec 17, 2002 |
| Priority date | — |
| Expiry date | Nov 5, 2019 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2770/10034
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention provides antigenic sites of PRRSV isolates. The antigenic sites are neutralizing, conserved, non-conserved and conformational, can elicit antibodies and are found on protein GP4 and N encoded ORF4 and ORF7 of PRRSV. The peptide sequences identified by the sites can be incorporated in vaccines directed against PRRS and in diagnostic tests for PRRS. Also, discriminating tests can be developed that can be used next to marker vaccines in programs designed to eradicate PRRS from pig herds.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.