Botulinum neurotoxin vaccine

US6495143B2 · kind B2 · utility

Assignee

• The United States of America as represented by the Secretary of the Army · US

Inventors

• John S. Lee · Hagerstown, US
• Peter Pushko · Frederick, US
• Jonathan F. Smith · Cary, US
• Michael Parker · Frederick, US
• Mark T. Dertzbaugh · Fairfield, US
• Leonard A. Smith · Clarksburg, US

Key dates

• Filing date: Jul 9, 1999
• Grant date: Dec 17, 2002
• Expiry date: Jul 9, 2019

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12N2799/021
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Using the nontoxic heavy chain fragment from botulinum neurotoxins A-G, compositions and methods of use in inducing an immune response which is protective against intoxication with botulinum in subjects is described.