LktA deletion mutant of P. haemolytica

US6495145B2 · kind B2 · utility

Assignees

• The United States of America, as represented by the Secretary of Agriculture · US
• Biotechnology Research and Development Corporation · US

Inventors

• Robert E. Briggs · Boone, US
• Fred M. Tatum · Nevada, US

Key dates

• Filing date: Oct 19, 2001
• Grant date: Dec 17, 2002
• Expiry date: Nov 16, 2021

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12R2001/01
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Mutants of P. haemolytica provide excellent safety and efficacy when used as vaccines in ruminants, for example cattle, sheep, and goats, subject to pneumonic pasteurellosis. They can be administered by a variety of routes. Especially preferred is the use in animal feeds. The mutants are not reverting and contain no foreign DNA and no introduced antibiotic resistance genes.